Membrane-tethering of cytochrome c accelerates regulated cell death in yeast

Intrinsic apoptosis as a modality of regulated cell death is intimately linked to permeabilization of the outer mitochondrial membrane and subsequent release of the protein cytochrome c into the cytosol, where it can participate in caspase activation via apoptosome formation. Interestingly, cytochro...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Toth, Alexandra, Aufschnaiter, Andreas, Fedotovskaya, Olga, Dawitz, Hannah, Ädelroth, Pia, Büttner, Sabrina, Ott, Martin
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474732/
https://ncbi.nlm.nih.gov/pubmed/32892209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02920-0
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