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HARC as an open-shell strategy to bypass oxidative addition in Ullmann–Goldberg couplings

The copper-catalyzed arylation of unsaturated nitrogen heterocycles, known as the Ullmann–Goldberg coupling, is a valuable transformation for medicinal chemists, providing a modular disconnection for the rapid diversification of heteroaromatic cores. The utility of the coupling, however, has establi...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Lavagnino, Marissa N., Liang, Tao, MacMillan, David W. C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474632/
https://ncbi.nlm.nih.gov/pubmed/32817531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011831117
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