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Multiomic blood correlates of genetic risk identify presymptomatic disease alterations

Transitions from health to disease are characterized by dysregulation of biological networks under the influence of genetic and environmental factors, often over the course of years to decades before clinical symptoms appear. Understanding these dynamics has important implications for preventive med...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Wainberg, Michael, Magis, Andrew T., Earls, John C., Lovejoy, Jennifer C., Sinnott-Armstrong, Nasa, Omenn, Gilbert S., Hood, Leroy, Price, Nathan D.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474629/
https://ncbi.nlm.nih.gov/pubmed/32817414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001429117
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