Anacardic acid induces IL-33 and promotes remyelination in CNS

Given the known neuroreparative actions of IL-33 in experimental models of central nervous system (CNS) injury, we predicted that compounds which induce IL-33 are likely to promote remyelination. We found anacardic acid as a candidate molecule to serve as a therapeutic agent to promote remyelination...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Ljunggren-Rose, Åsa, Natarajan, Chandramohan, Matta, Pranathi, Pandey, Akansha, Upender, Isha, Sriram, Subramaniam
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474623/
https://ncbi.nlm.nih.gov/pubmed/32817520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2006566117
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