Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression

Toxic environmental carcinogens promote cancer via genotoxic and nongenotoxic pathways, but nongenetic mechanisms remain poorly characterized. Carcinogen-induced apoptosis may trigger escape from dormancy of microtumors by interfering with inflammation resolution and triggering an endoplasmic reticu...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Fishbein, Anna, Wang, Weicang, Yang, Haixia, Yang, Jun, Hallisey, Victoria M., Deng, Jianjun, Verheul, Sanne M. L., Hwang, Sung Hee, Gartung, Allison, Wang, Yuxin, Bielenberg, Diane R., Huang, Sui, Kieran, Mark W., Hammock, Bruce D., Panigrahy, Dipak
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474612/
https://ncbi.nlm.nih.gov/pubmed/32801214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007412117
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