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Rationale for the Advancement of PI3K Pathway Inhibitors for Personalized Chordoma Therapy

PURPOSE: Chordomas are rare and serious tumors with few effective treatments outside of aggressive surgery and radiation. Targeted therapies may present a more effective option for a subset of patients with lesions possessing certain genetic biomarkers. METHODS: A small molecule inhibitor library wa...

詳細記述

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書誌詳細
出版年:J Neurooncol
主要な著者: Michmerhuizen, N.L., Owen, J.H., Heft Neal, M.E., Mann, J.E., Leonard, E., Wang, J., Zhai, J., Jiang, H., McHugh, J.B., Brenner, J.C., Prince, M.E.P.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474463/
https://ncbi.nlm.nih.gov/pubmed/32067197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-020-03418-7
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