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Current Status and Challenges of DNA Base Editing Tools
CRISPR-mediated DNA base editors, which include cytosine base editors (CBEs) and adenine base editors (ABEs), are promising tools that can induce point mutations at desired sites in a targeted manner to correct or disrupt gene expression. Their high editing efficiency, coupled with their ability to...
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| Publicado no: | Mol Ther |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Gene & Cell Therapy
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7474268/ https://ncbi.nlm.nih.gov/pubmed/32763143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.07.021 |
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