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Inhibition of central activation of the diaphragm: a mechanism of weaning failure

During a T-tube trial following disconnection of mechanical ventilation, patients failing the trial do not develop contractile diaphragmatic fatigue despite increases in inspiratory pressure output. Studies in volunteers, patients, and animals raise the possibility of spinal and supraspinal reflex m...

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Detalhes bibliográficos
Publicado no:J Appl Physiol (1985)
Main Authors: Laghi, Franco, Shaikh, Hameeda, Littleton, Stephen W., Morales, Daniel, Jubran, Amal, Tobin, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473953/
https://ncbi.nlm.nih.gov/pubmed/32673161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00856.2019
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