Reactive oxygen species oxidize STING and suppress interferon production

Reactive oxygen species (ROS) are by-products of cellular respiration that can promote oxidative stress and damage cellular proteins and lipids. One canonical role of ROS is to defend the cell against invading bacterial and viral pathogens. Curiously, some viruses, including herpesviruses, thrive de...

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Publicat a:eLife
Autors principals: Tao, Lili, Lemoff, Andrew, Wang, Guoxun, Zarek, Christina, Lowe, Alexandria, Yan, Nan, Reese, Tiffany A
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Immunology and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473769/
https://ncbi.nlm.nih.gov/pubmed/32886065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57837
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