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Temporal-specific roles of fragile X mental retardation protein in the development of the hindbrain auditory circuit

Fragile X mental retardation protein (FMRP) is an RNA-binding protein abundant in the nervous system. Functional loss of FMRP leads to sensory dysfunction and severe intellectual disabilities. In the auditory system, FMRP deficiency alters neuronal function and synaptic connectivity and results in p...

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Vydáno v:Development
Hlavní autoři: Wang, Xiaoyu, Kohl, Ayelet, Yu, Xiaoyan, Zorio, Diego A. R., Klar, Avihu, Sela-Donenfeld, Dalit, Wang, Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473654/
https://ncbi.nlm.nih.gov/pubmed/32747436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.188797
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