Fgfbp1 promotes blood-brain barrier development by regulating collagen IV deposition and maintaining Wnt/β-catenin signaling

Central nervous system (CNS) blood vessels contain a functional blood-brain barrier (BBB) that is necessary for neuronal survival and activity. Although Wnt/β-catenin signaling is essential for BBB development, its downstream targets within the neurovasculature remain poorly understood. To identify...

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Publicado en:Development
Autores principales: Cottarelli, Azzurra, Corada, Monica, Beznoussenko, Galina V., Mironov, Alexander A., Globisch, Maria A., Biswas, Saptarshi, Huang, Hua, Dimberg, Anna, Magnusson, Peetra U., Agalliu, Dritan, Lampugnani, Maria Grazia, Dejana, Elisabetta
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473640/
https://ncbi.nlm.nih.gov/pubmed/32747434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.185140
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