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In vitro activity of the first-in-class triazaacenaphthylene gepotidacin alone and in combination with doxycycline against drug-resistant and -susceptible Mycoplasma genitalium

Mycoplasma genitalium has developed resistance to first-line azithromycin and second-line moxifloxacin. Third-line pristinamycin is only 75% effective. Gepotidacin, a novel triazaacenaphthylene topoisomerase II inhibitor, blocks bacterial DNA replication. We determined the in vitro activity of gepot...

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書目詳細資料
發表在:Emerg Microbes Infect
Main Authors: Jensen, Jørgen Skov, Nørgaard, Christina, Scangarella-Oman, Nicole, Unemo, Magnus
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473033/
https://ncbi.nlm.nih.gov/pubmed/32552547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2020.1775498
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