SNX9 Inhibits Cell Proliferation and Cyst Development in Autosomal Dominant Polycystic Kidney Disease via Activation of the Hippo-YAP Signaling Pathway

Autosomal dominant polycystic kidney disease (ADPKD) is a complex process, involving the alteration of multiple genes and signaling pathways, and the pathogenesis of ADPKD remains largely unknown. Here, we demonstrated the suppressive role of sorting nexin 9 (SNX9) during ADPKD development. Sorting...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Shen, Ai-Wen, Fu, Li-Li, Lin, Lu, Sun, Bo, Song, Dong-Xu, Wang, Wu-Tao, Wang, Yi-Hao, Yin, Pei-Ran, Yu, Sheng-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472854/
https://ncbi.nlm.nih.gov/pubmed/32974348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00811
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