Targeting SREBP-2-Regulated Mevalonate Metabolism for Cancer Therapy

Recently, targeting metabolic reprogramming has emerged as a potential therapeutic approach for fighting cancer. Sterol regulatory element binding protein-2 (SREBP-2), a basic helix-loop-helix leucine zipper transcription factor, mainly regulates genes involved in cholesterol biosynthesis and homeos...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Xue, Linyuan, Qi, Hongyu, Zhang, He, Ding, Lu, Huang, Qingxia, Zhao, Daqing, Wu, Boyang Jason, Li, Xiangyan
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Oncology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472741/
https://ncbi.nlm.nih.gov/pubmed/32974183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01510
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