CDE-1 suppresses the production of risiRNA by coupling polyuridylation and degradation of rRNA

BACKGROUND: Modification of RNAs, particularly at the terminals, is critical for various essential cell processes; for example, uridylation is implicated in tumorigenesis, proliferation, stem cell maintenance, and immune defense against viruses and retrotransposons. Ribosomal RNAs can be regulated b...

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Bibliographic Details
Published in:BMC Biol
Main Authors: Wang, Yun, Weng, Chenchun, Chen, Xiangyang, Zhou, Xufei, Huang, Xinya, Yan, Yonghong, Zhu, Chengming
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472701/
https://ncbi.nlm.nih.gov/pubmed/32887607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00850-z
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