Whole-transcriptome Analysis of Fully Viable Energy Efficient Glycolytic-null Cancer Cells Established by Double Genetic Knockout of Lactate Dehydrogenase A/B or Glucose-6-Phosphate Isomerase

Background/Aim: Nearly all mammalian tumors of diverse tissues are believed to be dependent on fermentative glycolysis, marked by elevated production of lactic acid and expression of glycolytic enzymes, most notably lactic acid dehydrogenase (LDH). Therefore, there has been significant interest in d...

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Detalhes bibliográficos
Publicado no:Cancer Genomics Proteomics
Main Authors: MAZZIO, ELIZABETH, BADISA, RAMESH, MACK, NZINGA, CASSIM, SHAMIR, ZDRALEVIC, MASA, POUYSSEGUR, JACQUES, SOLIMAN, KARAM F.A.
Formato: Artigo
Idioma:Inglês
Publicado em: International Institute of Anticancer Research 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472444/
https://ncbi.nlm.nih.gov/pubmed/32859627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20205
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