Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation

Inhibition of platelet reactivity is a common therapeutic strategy in secondary prevention of cardiovascular disease. Genetic and environmental factors influence inter-individual variation in platelet reactivity. Identifying genes that contribute to platelet reactivity can reveal new biological mech...

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Bibliografiska uppgifter
I publikationen:Thromb Haemost
Huvudupphovsmän: Eicher, John D., Chen, Ming-Huei, Pitsillides, Achilleas N., Lin, Honghuang, Veeraraghavan, Narayanan, Brody, Jennifer A., Metcalf, Ginger A., Muzny, Donna M., Gibbs, Richard A., Becker, Diane M., Becker, Lewis C., Faraday, Nauder, Mathias, Rasika A., Yanek, Lisa R., Boerwinkle, Eric, Cupples, L. Adrienne, Johnson, Andrew D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472427/
https://ncbi.nlm.nih.gov/pubmed/28300864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH16-09-0677
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