Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation

Inhibition of platelet reactivity is a common therapeutic strategy in secondary prevention of cardiovascular disease. Genetic and environmental factors influence inter-individual variation in platelet reactivity. Identifying genes that contribute to platelet reactivity can reveal new biological mech...

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Detalhes bibliográficos
Publicado no:Thromb Haemost
Main Authors: Eicher, John D., Chen, Ming-Huei, Pitsillides, Achilleas N., Lin, Honghuang, Veeraraghavan, Narayanan, Brody, Jennifer A., Metcalf, Ginger A., Muzny, Donna M., Gibbs, Richard A., Becker, Diane M., Becker, Lewis C., Faraday, Nauder, Mathias, Rasika A., Yanek, Lisa R., Boerwinkle, Eric, Cupples, L. Adrienne, Johnson, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472427/
https://ncbi.nlm.nih.gov/pubmed/28300864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH16-09-0677
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