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Structural and Biological Basis of Alphacoronavirus nsp1 Associated with Host Proliferation and Immune Evasion

Non-structural protein 1 (nsp1) is only characterized in alphacoronaviruses (α-CoVs) and betacoronaviruses (β-CoVs). There have been extensive researches on how the β-CoVs nsp1 regulates viral virulence by inhibiting host protein synthesis, but the regulatory mechanism of the α-CoVs nsp1 is still un...

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Dades bibliogràfiques
Publicat a:Viruses
Autors principals: Shen, Zhou, Yang, Yiling, Yang, Siqi, Zhang, Guangxu, Xiao, Shaobo, Fu, Zhen F., Peng, Guiqing
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472224/
https://ncbi.nlm.nih.gov/pubmed/32731335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12080812
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