Scavenging Intracellular ROS Attenuates p-Cresyl Sulfate-Triggered Osteogenesis through MAPK Signaling Pathway and NF-κB Activation in Human Arterial Smooth Muscle Cells

Osteogenesis in human arterial smooth muscle cell (HASMC) is a key feature of uremic vascular calcification (UVC). Concerning pro-oxidant properties of p-cresyl sulfate (PCS), the therapeutic effect of reactive oxygen species (ROS) scavenger on PCS triggered inflammatory signaling transduction in os...

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Pubblicato in:Toxins (Basel)
Autori principali: Chang, Jia-Feng, Hsieh, Chih-Yu, Liou, Jian-Chiun, Liu, Shih-Hao, Hung, Chi-Feng, Lu, Kuo-Cheng, Lin, Chih-Cheng, Wu, Chang-Chin, Ka, Shuk-Man, Wen, Li-Li, Wu, Mai-Szu, Zheng, Cai-Mei, Ko, Wen-Chin
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472002/
https://ncbi.nlm.nih.gov/pubmed/32722241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12080472
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