Towards personalized induction therapy for esophageal adenocarcinoma: organoids derived from endoscopic biopsy recapitulate the pre-treatment tumor

Esophageal adenocarcinoma has few known recurrent mutations and therefore robust, reliable and reproducible patient-specific models are needed for personalized treatment. Patient-derived organoid culture is a strategy that may allow for the personalized study of esophageal adenocarcinoma and the dev...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Derouet, Mathieu F., Allen, Jonathan, Wilson, Gavin W., Ng, Christine, Radulovich, Nikolina, Kalimuthu, Sangeetha, Tsao, Ming-Sound, Darling, Gail E., Yeung, Jonathan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471705/
https://ncbi.nlm.nih.gov/pubmed/32884042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71589-4
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