Development of humanized mouse and rat models with full-thickness human skin and autologous immune cells

The human skin is a significant barrier for protection against pathogen transmission. Rodent models used to investigate human-specific pathogens that target the skin are generated by introducing human skin grafts to immunocompromised rodent strains. Infection-induced immunopathogenesis has been sepa...

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Foilsithe in:Sci Rep
Main Authors: Agarwal, Yash, Beatty, Cole, Ho, Sara, Thurlow, Lance, Das, Antu, Kelly, Samantha, Castronova, Isabella, Salunke, Rajeev, Biradar, Shivkumar, Yeshi, Tseten, Richardson, Anthony, Bility, Moses
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471691/
https://ncbi.nlm.nih.gov/pubmed/32884084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71548-z
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