The MeCP2E1/E2-BDNF-miR132 Homeostasis Regulatory Network Is Region-Dependent in the Human Brain and Is Impaired in Rett Syndrome Patients

Rett Syndrome (RTT) is a rare and progressive neurodevelopmental disorder that is caused by de novo mutations in the X-linked Methyl CpG binding protein 2 (MECP2) gene and is subjected to X-chromosome inactivation. RTT is commonly associated with neurological regression, autistic features, motor con...

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Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Pejhan, Shervin, Del Bigio, Marc R., Rastegar, Mojgan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471663/
https://ncbi.nlm.nih.gov/pubmed/32974336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00763
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