Plasma Membrane Pores Drive Inflammatory Cell Death

Necroptosis and pyroptosis are two forms of regulated cell death. They are executed by the proteins mixed-lineage kinase domain-like (MLKL) and gasdermin D (GSDMD), respectively. Once activated by numerous pathways, these proteins form membrane pores that allow the influx and efflux of various ions,...

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Udgivet i:Front Cell Dev Biol
Main Authors: Kolbrink, Benedikt, Riebeling, Theresa, Kunzendorf, Ulrich, Krautwald, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471660/
https://ncbi.nlm.nih.gov/pubmed/32974349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00817
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