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Daprodustat: First Approval
Daprodustat (DUVROQ) is a small molecule inhibitor of hypoxia-inducible factor prolyl hydroxylase (PHD) developed by GlaxoSmithKline for the treatment of anaemia in patients with chronic kidney disease (CKD). Inhibition of PHD prevents degradation of hypoxia-inducible factor (HIF), leading to the pr...
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| Publicado no: | Drugs |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7471535/ https://ncbi.nlm.nih.gov/pubmed/32880805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40265-020-01384-y |
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