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Garcinol inhibits esophageal cancer metastasis by suppressing the p300 and TGF-β1 signaling pathways

Metastasis causes the main lethality in esophageal cancer patient. Garcinol, a natural compound extracted from Gambogic genera, is a histone acetyltransferase (HAT) inhibitor that has shown anticancer activities such as cell cycle arrest and apoptosis induction. In this study, we investigated the ef...

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Publicado en:Acta Pharmacol Sin
Autores principales: Wang, Jing, Wu, Man, Zheng, Dan, Zhang, Hong, Lv, Yue, Zhang, Li, Tan, Hong-sheng, Zhou, Hua, Lao, Yuan-zhi, Xu, Hong-xi
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Singapore 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471459/
https://ncbi.nlm.nih.gov/pubmed/31371781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0271-3
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