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GFPT2 promotes metastasis and forms a positive feedback loop with p65 in colorectal cancer

As a rate-limiting enzyme of the hexosamine biosynthesis pathway (HBP), which is responsible for glycosylation, Glutamine fructose-6-phosphate amidotransferase 2 (GFPT2) is involved in human breast and lung tumorigenesis. However, whether GFTP2 is associated with tumor metastasis remains unclear. He...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Liu, Lixin, Pan, Yangjian, Ren, Xiaoli, Zeng, Zhicheng, Sun, Jingbo, Zhou, Kun, Liang, Yunshi, Wang, Feifei, Yan, Yongrong, Liao, Wenting, Ding, Yanqing, Liu, Xiaolong, Liang, Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471343/
https://ncbi.nlm.nih.gov/pubmed/32905539
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