Suprabasin-null mice retain skin barrier function and show high contact hypersensitivity to nickel upon oral nickel loading

Suprabasin (SBSN) is expressed not only in epidermis but also in epithelial cells of the upper digestive tract where metals such as nickel are absorbed. We have recently shown that SBSN level is decreased in the stratum corneum and serum of atopic dermatitis (AD) patients, especially in intrinsic AD...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakazawa, Shinsuke, Shimauchi, Takatoshi, Funakoshi, Atsuko, Aoshima, Masahiro, Phadungsaksawasdi, Pawit, Sakabe, Jun-ichi, Asakawa, Sanki, Hirasawa, Noriyasu, Ito, Taisuke, Tokura, Yoshiki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471289/
https://ncbi.nlm.nih.gov/pubmed/32884021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71536-3
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