Computational and experimental characterization of estrogenic activities of 20(S, R)-protopanaxadiol and 20(S, R)-protopanaxatriol

BACKGROUND: As the main metabolites of ginsenosides, 20(S, R)-protopanaxadiol [PPD(S, R)] and 20(S, R)-protopanaxatriol [PPT(S, R)] are the structural basis response to a series of pharmacological effects of their parent components. Although the estrogenicity of several ginsenosides has been confirm...

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Bibliographic Details
Published in:J Ginseng Res
Main Authors: Zhang, Tiehua, Zhong, Shuning, Hou, Ligang, Wang, Yongjun, Xing, XiaoJia, Guan, Tianzhu, Zhang, Jie, Li, Tiezhu
Format: Artigo
Language:Inglês
Published: Elsevier 2020
Subjects:
Pharmacology & Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471209/
https://ncbi.nlm.nih.gov/pubmed/32913398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgr.2018.05.001
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