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MiR-542-5p Inhibits Hyperglycemia and Hyperlipoidemia by Targeting FOXO1 in the Liver

PURPOSE: This research was designed to investigate how miR-542-5p regulates the progression of hyperglycemia and hyperlipoidemia. MATERIALS AND METHODS: An in vivo model with diabetic db/db mice and an in vitro model with forskolin/dexamethasone (FSK/DEX)-induced primary hepatocytes and HepG2 cells...

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Pubblicato in:Yonsei Med J
Autori principali: Tian, Fang, Ying, Hui-Min, Wang, Yuan-Yuan, Cheng, Bo-Ning, Chen, Juan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Yonsei University College of Medicine 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471073/
https://ncbi.nlm.nih.gov/pubmed/32882762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2020.61.9.780
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