Mechanism of translation inhibition by type II GNAT toxin AtaT2

Type II toxin–antitoxins systems are widespread in prokaryotic genomes. Typically, they comprise two proteins, a toxin, and an antitoxin, encoded by adjacent genes and forming a complex in which the enzymatic activity of the toxin is inhibited. Under stress conditions, the antitoxin is degraded libe...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Ovchinnikov, Stepan V, Bikmetov, Dmitry, Livenskyi, Alexei, Serebryakova, Marina, Wilcox, Brendan, Mangano, Kyle, Shiriaev, Dmitrii I, Osterman, Ilya A, Sergiev, Petr V, Borukhov, Sergei, Vazquez-Laslop, Nora, Mankin, Alexander S, Severinov, Konstantin, Dubiley, Svetlana
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
RNA and RNA-protein complexes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470980/
https://ncbi.nlm.nih.gov/pubmed/32597957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa551
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