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RNA aptamer capture of macromolecular complexes for mass spectrometry analysis

Specific genomic functions are dictated by macromolecular complexes (MCs) containing multiple proteins. Affinity purification of these complexes, often using antibodies, followed by mass spectrometry (MS) has revolutionized our ability to identify the composition of MCs. However, conventional immuno...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Ray, Judhajeet, Kruse, Angela, Ozer, Abdullah, Kajitani, Takuya, Johnson, Richard, MacCoss, Michael, Heck, Michelle, Lis, John T
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470977/
https://ncbi.nlm.nih.gov/pubmed/32609809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa542
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