Intact RNA structurome reveals mRNA structure-mediated regulation of miRNA cleavage in vivo

MicroRNA (miRNA)-mediated cleavage is involved in numerous essential cellular pathways. miRNAs recognize target RNAs via sequence complementarity. In addition to complementarity, in vitro and in silico studies have suggested that RNA structure may influence the accessibility of mRNAs to miRNA-induce...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Yang, Minglei, Woolfenden, Hugh C, Zhang, Yueying, Fang, Xiaofeng, Liu, Qi, Vigh, Maria L, Cheema, Jitender, Yang, Xiaofei, Norris, Matthew, Yu, Sha, Carbonell, Alberto, Brodersen, Peter, Wang, Jiawei, Ding, Yiliang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470952/
https://ncbi.nlm.nih.gov/pubmed/32652041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa577
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