Conditional kisspeptin neuron-specific Kiss1 knockout with newly generated Kiss1-floxed and Kiss1-Cre mice replicates a hypogonadal phenotype of global Kiss1 knockout mice

The present study aimed to evaluate whether novel conditional kisspeptin neuron-specific Kiss1 knockout (KO) mice utilizing the Cre-loxP system could recapitulate the infertility of global Kiss1 KO models, thereby providing further evidence for the fundamental role of hypothalamic kisspeptin neurons...

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Udgivet i:J Reprod Dev
Main Authors: IKEGAMI, Kana, GOTO, Teppei, NAKAMURA, Sho, WATANABE, Youki, SUGIMOTO, Arisa, MAJARUNE, Sutisa, HORIHATA, Kei, NAGAE, Mayuko, TOMIKAWA, Junko, IMAMURA, Takuya, SANBO, Makoto, HIRABAYASHI, Masumi, INOUE, Naoko, MAEDA, Kei-ichiro, TSUKAMURA, Hiroko, UENOYAMA, Yoshihisa
Format: Artigo
Sprog:Inglês
Udgivet: The Society for Reproduction and Development 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470906/
https://ncbi.nlm.nih.gov/pubmed/32307336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2020-026
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