Peripheral administration of SB223412, a selective neurokinin-3 receptor antagonist, suppresses pulsatile luteinizing hormone secretion by acting on the gonadotropin-releasing hormone pulse generator in estrogen-treated ovariectomized female goats

Accumulating evidence suggests that KNDy neurons located in the hypothalamic arcuate nucleus (ARC), which are reported to express kisspeptin, neurokinin B, and dynorphin A, are indispensable for the gonadotropin-releasing hormone (GnRH) pulse generation that results in rhythmic GnRH secretion. The a...

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Detalhes bibliográficos
Publicado no:J Reprod Dev
Main Authors: SASAKI, Takuya, SONODA, Tomoya, TATEBAYASHI, Ryoki, KITAGAWA, Yuri, OISHI, Shinya, YAMAMOTO, Koki, FUJII, Nobutaka, INOUE, Naoko, UENOYAMA, Yoshihisa, TSUKAMURA, Hiroko, MAEDA, Kei-ichiro, MATSUDA, Fuko, MORITA, Yasuhiro, MATSUYAMA, Shuichi, OHKURA, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Reproduction and Development 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470901/
https://ncbi.nlm.nih.gov/pubmed/32281549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2019-145
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