EGFR and KRAS mutation analysis in cytologic samples of lung adenocarcinoma enabled by laser capture microdissection

The discovery of activating mutations in EGFR and KRAS in a subset of lung adenocarcinomas was a major advance in our understanding of lung adenocarcinoma biology, and has led to groundbreaking studies that have demonstrated the efficacy of tyrosine kinase inhibitor therapy. Fine-needle aspirates an...

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Pubblicato in:Mod Pathol
Autori principali: Chowdhuri, Sinchita Roy, Xi, Liqiang, Pham, Trinh Hoc-Tran, Hanson, Jeffrey, Rodriguez-Canales, Jaime, Berman, Arlene, Rajan, Arun, Giaccone, Giuseppe, Emmert-Buck, Michael, Raffeld, Mark, Filie, Armando C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470622/
https://ncbi.nlm.nih.gov/pubmed/22157931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2011.184
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