Influence of beta-cluster haplotypes, alpha-gene status and UGTA1 polymorphism on clinical and hematological data in sickle-cell disease children from French Guiana

OBJECTIVES: This cross-sectional study aimed to investigate the influence of haplotypes, alpha-gene status and UGTA1 polymorphism on the severity of sickle cell disease in children. METHODS: This cross-sectional study was conducted between 2012 and 2014 at the Cayenne Hospital, in French Guiana. Acu...

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Bibliographic Details
Published in:PLoS One
Main Authors: Elenga, Narcisse, Cuadro-Alvarez, Emma, Martin, Elise, Njuieyon, Falucar, Defo, Antoine, Maniassom, Chimène
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470392/
https://ncbi.nlm.nih.gov/pubmed/32881938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0238691
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