Antioxidant effect of acetyl-l-carnitine against cisplatin-induced cardiotoxicity

OBJECTIVE: Cisplatin (CDDP) toxicity is a dose-limiting clinical problem in clinical practice, mainly because of nephrotoxicity or ototoxicity. However, the mechanism of CDDP-induced cardiotoxicity is poorly understood. Acetyl-l-carnitine (ALCAR) is an antioxidant agent with protective effects again...

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Udgivet i:J Int Med Res
Main Authors: Bayrak, Serdar, Aktaş, Safiye, Altun, Zekiye, Çakir, Yasemin, Tütüncü, Merve, Kum Özşengezer, Selen, Yilmaz, Osman, Olgun, Nur
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2020
Fag:
Pre-Clinical Research Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469739/
https://ncbi.nlm.nih.gov/pubmed/32865065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060520951393
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