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New tricks of an old autophagy regulator: AMPK-dependent regulation of autophagy through CCNY (cyclin Y)-CDK16

AMPK is one of the main regulators of energy homeostasis in the cell, achieving this role in part by upregulating autophagy in times of nutrient deprivation. Previous reports have described several AMPK substrates involved in autophagy regulation; however, there are still undiscovered AMPK downstrea...

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Vydáno v:Autophagy
Hlavní autoři: Gatica, Damián, Klionsky, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469459/
https://ncbi.nlm.nih.gov/pubmed/32401167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1756665
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