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FDA orphan products clinical trial grants: assessment of outcomes and impact on rare disease product development

BACKGROUND: The Office of Orphan Products Development (OOPD) of the United States (U.S.) Food and Drug Administration (FDA) has awarded over 700 grants to conduct clinical trials of medicals products for rare diseases since 1983, leading to over 70 marketing approvals. However, despite recent progre...

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Detalhes bibliográficos
Publicado no:Orphanet J Rare Dis
Main Authors: Miller, Kathleen L., Mueller, Christine, Liu, Gumei, Miller Needleman, Katherine I., Maynard, Janet
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469294/
https://ncbi.nlm.nih.gov/pubmed/32883327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-020-01514-5
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