Diet-induced obesity exacerbates imiquimod-mediated psoriasiform dermatitis in anti-PD-1 antibody-treated mice: Implications for patients being treated with checkpoint inhibitors for cancer

BACKGROUND: An ever-increasing number of cancer patients are being treated with checkpoint inhibitors such as anti-PD-1 antibodies, and a small percentage of these patients develop a psoriasis-like skin eruption or severe flares of prior psoriasis. OBJECTIVE: We investigated the role of obesity in i...

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Vydáno v:J Dermatol Sci
Hlavní autoři: Yu, Sebastian, Wu, Xuesong, Shi, Zhenrui, Huynh, Mindy, Jena, Prasant Kumar, Sheng, Lili, Zhou, Yan, Han, Dan, Wan, Yu-Jui Yvonne, Hwang, Samuel T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469262/
https://ncbi.nlm.nih.gov/pubmed/32044178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdermsci.2020.01.011
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