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Catalytic Mechanism of Processive GlfT2: Transition Path Sampling Investigation of Substrate Translocation

[Image: see text] We applied the transition path sampling (TPS) method to study the translocation step of the catalytic mechanism of galactofuranosyl transferase 2 (GlfT2). Using TPS in the field of enzymatic reactions is still relatively rare, and we show its effectiveness on this enzymatic system....

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Veröffentlicht in:ACS Omega
Hauptverfasser: Janoš, Pavel, Tvaroška, Igor, Dellago, Christoph, Koča, Jaroslav
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2020
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469130/
https://ncbi.nlm.nih.gov/pubmed/32905330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c01434
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