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Desaturase Activity and the Risk of Type 2 Diabetes and Coronary Artery Disease: A Mendelian Randomization Study

Estimated Δ5-desaturase (D5D) and Δ6-desaturase (D6D) are key enzymes in metabolism of polyunsaturated fatty acids (PUFA) and have been associated with cardiometabolic risk; however, causality needs to be clarified. We applied two-sample Mendelian randomization (MR) approach using a representative s...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Jäger, Susanne, Cuadrat, Rafael, Hoffmann, Per, Wittenbecher, Clemens, Schulze, Matthias B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469057/
https://ncbi.nlm.nih.gov/pubmed/32731631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12082261
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