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Mechanism of Action of Ketogenic Diet Treatment: Impact of Decanoic Acid and Beta—Hydroxybutyrate on Sirtuins and Energy Metabolism in Hippocampal Murine Neurons

The ketogenic diet (KD), a high-lipid and low-carbohydrate diet, has been used in the treatment of epilepsy, neurodegenerative disorders, inborn errors of metabolism and cancer; however, the exact mechanism/s of its therapeutic effect is not completely known. We hypothesized that sirtuins (SIRT)—a g...

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Bibliographic Details
Published in:Nutrients
Main Authors: Dabke, Partha, Das, Anibh M.
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468807/
https://ncbi.nlm.nih.gov/pubmed/32784510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12082379
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