Urotensin II and urantide exert opposite effects on the cellular components of atherosclerotic plaque in hypercholesterolemic rabbits

Increasing levels of plasma urotensin II (UII) are positively associated with atherosclerosis. In this study we investigated the role of macrophage-secreted UII in atherosclerosis progression, and evaluated the therapeutic value of urantide, a potent competitive UII receptor antagonist, in atheroscl...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Yu, Qing-qing, Cheng, Da-xin, Xu, Li-ran, Li, Yan-kui, Zheng, Xiao-ya, Liu, Yi, Li, Ya-feng, Liu, Hao-le, Bai, Liang, Wang, Rong, Fan, Jiang-lin, Liu, En-qi, Zhao, Si-hai
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468446/
https://ncbi.nlm.nih.gov/pubmed/31685976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0315-8
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