Neuroprotective effects of olanzapine against rotenone-induced toxicity in PC12 cells

Olanzapine is an antipsychotic drug used to treat patients with schizophrenia due to its lower incidence of extrapyramidal symptoms. Previous studies have shown that olanzapine activates AMP-activated protein kinase (AMPK), and induce autophagy in SH-SY5Y cell line. In this study, we investigated wh...

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Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Xiong, Ya-jie, Song, Yun-zhen, Zhu, Ying, Zuo, Wen-qing, Zhao, Yi-fan, Shen, Xiao, Wang, Wen-juan, Liu, Ya-li, Wu, Jun-chao, Liang, Zhong-qin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Singapore 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468335/
https://ncbi.nlm.nih.gov/pubmed/32123301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0378-6
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