Potential of platinum-resensitization by Wnt signaling modulators as treatment approach for epithelial ovarian cancer

PURPOSE: Canonical Wnt/ β-catenin pathway is one mechanism being activated in platinum-resistant epithelial ovarian cancer (EOC). Detecting potential targets for Wnt pathway modulation as a putative future therapeutic approach was the aim of this study. METHODS: Biological effects of different Wnt m...

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Dettagli Bibliografici
Pubblicato in:J Cancer Res Clin Oncol
Autori principali: Kaltofen, Till, Preinfalk, Valentina, Schwertler, Stephanie, Fraungruber, Patricia, Heidegger, Helene, Vilsmaier, Theresa, Vattai, Aurelia, Czogalla, Bastian, Mayr, Doris, Mahner, Sven, Jeschke, Udo, Trillsch, Fabian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2020
Soggetti:
Original Article – Cancer Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467966/
https://ncbi.nlm.nih.gov/pubmed/32681294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-020-03317-4
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