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Preclinical Pharmacokinetic/Pharmacodynamic Studies and Clinical Trials in the Drug Development Process of EMA-Approved Antibacterial Agents: A Review

Development of new antibacterial agents is necessary as drug-resistant bacteria are a threat to global health. In Europe, the European Medicines Agency has been guiding this development process for more than two decades. We investigated preclinical and clinical pre-approval studies to illuminate the...

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Detalhes bibliográficos
Publicado no:Clin Pharmacokinet
Main Authors: Jorda, Anselm, Zeitlinger, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467913/
https://ncbi.nlm.nih.gov/pubmed/32356105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-020-00892-0
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