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The dynamic nature of the human origin recognition complex revealed through five cryoEM structures
Genome replication is initiated from specific origin sites established by dynamic events. The Origin Recognition Complex (ORC) is necessary for orchestrating the initiation process by binding to origin DNA, recruiting CDC6, and assembling the MCM replicative helicase on DNA. Here we report five cryo...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7467728/ https://ncbi.nlm.nih.gov/pubmed/32808929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58622 |
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