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mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex

Outer radial glial (oRG) cells are a population of neural stem cells prevalent in the developing human cortex that contribute to its cellular diversity and evolutionary expansion. The mammalian Target of Rapamycin (mTOR) signaling pathway is active in human oRG cells. Mutations in mTOR pathway genes...

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Publicat a:eLife
Autors principals: Andrews, Madeline G, Subramanian, Lakshmi, Kriegstein, Arnold R
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467727/
https://ncbi.nlm.nih.gov/pubmed/32876565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58737
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