Antagonistic control of Caenorhabditis elegans germline stem cell proliferation and differentiation by PUF proteins FBF-1 and FBF-2

Stem cells support tissue maintenance, but the mechanisms that coordinate the rate of stem cell self-renewal with differentiation at a population level remain uncharacterized. We find that two PUF family RNA-binding proteins FBF-1 and FBF-2 have opposite effects on Caenorhabditis elegans germline st...

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Veröffentlicht in:eLife
Hauptverfasser: Wang, Xiaobo, Ellenbecker, Mary, Hickey, Benjamin, Day, Nicholas J, Osterli, Emily, Terzo, Mikaya, Voronina, Ekaterina
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2020
Schlagworte:
Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467723/
https://ncbi.nlm.nih.gov/pubmed/32804074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52788
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